Genetic dissection of acute anterior uveitis reveals similarities and differences in associations observed with ankylosing spondylitis.

doi:10.1002/art.38873

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Article

Genetic dissection of acute anterior uveitis reveals similarities and differences in associations observed with ankylosing spondylitis.

Arthritis & rheumatology (Hoboken, N.J.) - 1 Jan 2015

Robinson Philip C, Claushuis Theodora A M, Cortes Adrian, Martin Tammy M, Evans David M, Leo Paul, Mukhopadhyay Pamela, Bradbury Linda A, Cremin Katie, Harris Jessica, Maksymowych Walter P, Inman Robert D, Rahman Proton, Haroon Nigil, Gensler Lianne, Powell Joseph E, van der Horst-Bruinsma Irene E, Hewitt Alex W, Craig Jamie E, Lim Lyndell L, Wakefield Denis, McCluskey Peter, Voigt Valentina, Fleming Peter, Degli-Esposti Mariapia, Pointon Jennifer J, Weisman Michael H, Wordsworth B Paul, Reveille John D, Rosenbaum James T, Brown Matthew A

Abstract excerpt

OBJECTIVE: To use high-density genotyping to investigate the genetic associations of acute anterior uveitis (AAU) in patients with and those without ankylosing spondylitis (AS). METHODS: We genotyped samples from 1,711 patients with AAU (either primary or combined with AS), 2,339 AS patients without AAU, and 10,000 control subjects on an Illumina Immunochip Infinium microarray. We also used data for AS patients...

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PMID: 25200001
DOI: 10.1002/art.38873
PMCID: PMC4302162

Genes

ANTXR2
ERAP1
EYS

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