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Methylation in the Promoters of <i>HS3ST2</i> and <i>CCNA1</i> Genes is Associated with Cervical Cancer in Uygur Women in Xinjiang

12 Sept 2014

Abstract excerpt

We assessed the suitability of HS3ST2 and CCNA1 genes as biomarkers for the early detection of cervical cancer in Uygur women in Xinjiang, China. Methylation-specific PCR (MSP) and HPV (HPV16 and HPV18)-specific PCR were performed on 110 cervical samples: 40 normal cervices, 10 cervical intraepithelial neoplasia 1 (CIN1), 10 CIN2, 10 CIN3 and 40 cervical cancer tissues. The expression of the 2 genes was measured...

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PMID: 25198553
DOI: 10.5301/jbm.5000107

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