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Article

Autophagy, Warburg, and Warburg Reverse Effects in Human Cancer

1 Jan 2014

Abstract excerpt

Autophagy is a highly regulated-cell pathway for degrading long-lived proteins as well as for clearing cytoplasmic organelles. Autophagy is a key contributor to cellular homeostasis and metabolism. Warburg hypothesized that cancer growth is frequently associated with a deviation of a set of energy generation mechanisms to a nonoxidative breakdown of glucose. This cellular phenomenon seems to rely on a respiratory...

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Identifiers

PMID: 25197670
DOI: 10.1155/2014/926729

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