Article
Amino acid change in the carbohydrate response element binding protein is associated with lower triglycerides and myocardial infarction incidence depending on level of adherence to the Mediterranean diet in the PREDIMED trial.
Circulation. Cardiovascular genetics - 1 Feb 2014
Ortega-Azorín Carolina, Sorlí Jose V, Estruch Ramón, Asensio Eva M, Coltell Oscar, González José I, Martínez-González Miguel Ángel, Ros Emilio, Salas-Salvadó Jordi, Fitó Montserrat, Arós Fernando, Lapetra José, Serra-Majem Lluís, Ruiz-Gutiérrez Valentina, Gómez-Gracia Enrique, Fiol Miquel, Flores Gemma, Pintó Xavier, Saiz Carmen, Ordovás José M, Corella Dolores
Abstract excerpt
BACKGROUND: A variant (rs3812316, C771G, and Gln241His) in the MLXIPL (Max-like protein X interacting protein-like) gene encoding the carbohydrate response element binding protein has been associated with lower triglycerides. However, its association with cardiovascular diseases and gene-diet interactions modulating these traits are unknown. METHODS AND RESULTS: We studied 7166 participants in the PREvención with...
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