Article
Genomic characterization of non-mucus-adherent derivatives of Lactobacillus rhamnosus GG reveals genes affecting pilus biogenesis.
Applied and environmental microbiology - 1 Nov 2014
Rasinkangas Pia, Reunanen Justus, Douillard François P, Ritari Jarmo, Uotinen Virva, Palva Airi, de Vos Willem M
Abstract excerpt
Lactobacillus rhamnosus GG is one of the best-characterized lactic acid bacteria and can be considered a probiotic paradigm. Comparative and functional genome analysis showed that L. rhamnosus GG harbors a genomic island including the spaCBA-srtC1 gene cluster, encoding the cell surface-decorating host-interacting pili. Here, induced mutagenesis was used to study pilus biogenesis in L. rhamnosus GG. A combination...
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