Article
Functional analysis of Lactobacillus rhamnosus GG pili in relation to adhesion and immunomodulatory interactions with intestinal epithelial cells.
Applied and environmental microbiology - 1 Jan 2012
Lebeer Sarah, Claes Ingmar, Tytgat Hanne L P, Verhoeven Tine L A, Marien Eyra, von Ossowski Ingemar, Reunanen Justus, Palva Airi, Vos Willem M de, Keersmaecker Sigrid C J De, Vanderleyden Jos
Abstract excerpt
Lactobacillus rhamnosus GG, a probiotic with good survival capacity in the human gut, has well-documented adhesion properties and health effects. Recently, spaCBA-encoded pili that bind to human intestinal mucus were identified on its cell surface. Here, we report on the phenotypic analysis of a spaCBA pilus knockout mutant in comparison with the wild type and other adhesin mutants. The SpaCBA pilus of L....
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