Article
Uniaxial cyclic stretch promotes osteogenic differentiation and synthesis of BMP2 in the C3H10T1/2 cells with BMP2 gene variant of rs2273073 (T/G).
PloS one - 1 Jan 2014
Li Jia-mou, Zhang Yao, Ren Yuan, Liu Bao-ge, Lin Xin, Yang Jiang, Zhao Hu-cheng, Wang Ya-jie, Song Lei
Abstract excerpt
Ossification of the posterior longitudinal ligament of the cervical spine (OPLL) is characterized by the replacement of ligament tissues with ectopic bone formation, and this result is strongly affected by genetic and local factors. Two single nucleotide polymorphisms (SNPs) of rs2273073 (T/G) and rs235768 (A/T) of bone morphogenetic protein 2 (BMP2) gene which are associated with OPLL have been reported in our...
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