Article
A genome-wide association analysis for porcine serum lipid traits reveals the existence of age-specific genetic determinants.
BMC genomics - 4 Sept 2014
Manunza Arianna, Casellas Joaquim, Quintanilla Raquel, González-Prendes Rayner, Pena Ramona N, Tibau Joan, Mercadé Anna, Castelló Anna, Aznárez Nitdia, Hernández-Sánchez Jules, Amills Marcel
Abstract excerpt
BACKGROUND: The genetic determinism of blood lipid concentrations, the main risk factor for atherosclerosis, is practically unknown in species other than human and mouse. Even in model organisms, little is known about how the genetic determinants of lipid traits are modulated by age-specific factors. To gain new insights into this issue, we have carried out a genome-wide association study (GWAS) for cholesterol...
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