Article
Genome-Wide Association Analysis for Blood Lipid Traits Measured in Three Pig Populations Reveals a Substantial Level of Genetic Heterogeneity.
PloS one - 1 Jan 2015
Yang Hui, Huang Xiaochang, Zeng Zhijun, Zhang Wanchang, Liu Chenlong, Fang Shaoming, Huang Lusheng, Chen Congying
Abstract excerpt
Serum lipids are associated with myocardial infarction and cardiovascular disease in humans. Here we dissected the genetic architecture of blood lipid traits by applying genome-wide association studies (GWAS) in 1,256 pigs from Laiwu, Erhualian and Duroc × (Landrace × Yorkshire) populations, and a meta-analysis of GWAS in more than 2,400 pigs from five diverse populations. A total of 22 genomic loci surpassing...
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