Article
Docking studies of Pakistani HCV NS3 helicase: a possible antiviral drug target.
PloS one - 1 Jan 2014
Fatima Kaneez, Mathew Shilu, Suhail Mohd, Ali Ashraf, Damanhouri Ghazi, Azhar Esam, Qadri Ishtiaq
Abstract excerpt
The nonstructural protein 3 (NS3) of hepatitis C virus (HCV) helicase is believed to be essential for viral replication and has become an attractive target for the development of antiviral drugs. The study of helicase is useful for elucidating its involvement in positive sense single-stranded RNA virus replication and to serve as templates for the design of novel antiviral drugs. In recent years, several models...
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