Article
Development of robust in vitro serine protease assay based on recombinant Pakistani HCV NS3-4A protease.
Virus research - 1 Sept 2011
Fatima Kaneez, Tahir Muhammad, Qadri Ishtiaq
Abstract excerpt
Hepatitis C virus (HCV) infection is a serious cause of chronic liver disease worldwide with more than 170 million infected individuals at risk of developing significant morbidity and mortality. Current interferon-based therapies are suboptimal especially in patients infected with HCV genotype 3 (predominant genotype in Pakistan) and they are poorly tolerated, highlighting the requirement of new therapeutics. HCV...
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