Article
Hirano body expression impairs spatial working memory in a novel mouse model.
Acta neuropathologica communications - 2 Sept 2014
Furgerson Matthew, Clark Jason K, Crystal Jonathon D, Wagner John J, Fechheimer Marcus, Furukawa Ruth
Abstract excerpt
INTRODUCTION: Hirano bodies are actin-rich intracellular inclusions found in the brains of patients with neurodegenerative conditions such as Alzheimer's disease or frontotemporal lobar degeneration-tau. While Hirano body ultrastructure and protein composition have been well studied, little is kn...
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