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Article

Impact of metallothionein gene polymorphisms on the risk of lung cancer in a Japanese population.

Molecular carcinogenesis - 1 Jun 2015

Nakane Hideo, Hirano Minoru, Ito Hidemi, Hosono Satoyo, Oze Isao, Matsuda Fumihiko, Tanaka Hideo, Matsuo Keitaro

Abstract excerpt

Metallothioneins (MTs) are cysteine-rich proteins that act as antioxidants. A case-control study was conducted to assess the effects of gene polymorphisms in the MT region on the risk of lung cancer in Japanese subjects: 769 lung cancer cases and 939 non-cancer controls. Associations were evaluated using logistic regression models with adjustment for potential confounders (age, sex, and lifestyle factors...

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Identifiers

PMID: 25174824
DOI: 10.1002/mc.22198

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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