Article
Ovarian tumor-initiating cells display a flexible metabolism.
Experimental cell research - 15 Oct 2014
Anderson Angela S, Roberts Paul C, Frisard Madlyn I, Hulver Matthew W, Schmelz Eva M
Abstract excerpt
An altered metabolism during ovarian cancer progression allows for increased macromolecular synthesis and unrestrained growth. However, the metabolic phenotype of cancer stem or tumor-initiating cells, small tumor cell populations that are able to recapitulate the original tumor, has not been well characterized. In the present study, we compared the metabolic phenotype of the stem cell enriched cell variant,...
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