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Targeting cancer stem cells from a metabolic perspective

26 Feb 2020

Abstract excerpt

The process of cancer development and progression is driven by distinct subsets of cancer stem cells (CSCs) that contribute the self-renewal capacity as the major impetus to the metastatic dissemination and main impediments in cancer treatment. Given that CSCs are so scarce in the tumor mass, there are debatable points on the metabolic signatures of CSCs. As opposed to differentiated tumor progenies, CSCs display...

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PMID: 32102562
DOI: 10.1177/1535370220909309

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