Morphologic and cytogenetic differences between post-polycythemic myelofibrosis and primary myelofibrosis in fibrotic stage.

doi:10.1038/modpathol.2013.109

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Article

Morphologic and cytogenetic differences between post-polycythemic myelofibrosis and primary myelofibrosis in fibrotic stage.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Dec 2013

Boiocchi Leonardo, Mathew Susan, Gianelli Umberto, Iurlo Alessandra, Radice Tommaso, Barouk-Fox Sharon, Knowles Daniel M, Orazi Attilio

Abstract excerpt

Polycythemia vera and primary myelofibrosis share a propensity to progress toward a myelofibrotic late stage with overlapping clinical characteristics. Bone marrow features potentially useful for distinguishing the two entities have not been thoroughly investigated and, currently, clinical history is used for purposes of disease classification. This study describes in detail the morphologic features of 23 cases...

Topics

Abnormal Karyotype
Aged
Cytogenetic Analysis
Diagnosis, Differential
Female
Humans
Immunohistochemistry
Janus Kinase 2
Kaplan-Meier Estimate
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Megakaryocytes

Middle Aged

Mutation

Polycythemia Vera

Polymerase Chain Reaction

Primary Myelofibrosis

Source

Open in PubMed

Identifiers

PMID: 23787440
DOI: 10.1038/modpathol.2013.109

Genes

JAK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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