Article
Combined effect of Factor V Leiden, MTHFR, and angiotensin-converting enzyme (insertion/deletion) gene mutations in hypertensive adult individuals: a population-based study from Sivas and Canakkale, Turkey.
Genetic testing and molecular biomarkers - 1 Nov 2011
Demirel Yeltekin, Dogan Sezai, Uludag Ahmet, Silan Coskun, Atik Sinem, Silan Fatma, Ozdemir Ozturk
Abstract excerpt
BACKGROUND: Hypertension is one of the leading causes of mortality and morbidity in the world, which is influenced by environmental and genetic factors. The methylenetetrahydrofolate reductase (MTHFR) and angiotensin-converting enzymes (ACE) are possible candidate genes that may influence both body fatness and blood pressure (BP). The purpose of this study was to examine the carriage of gene combinations of the...
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