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Article

Use of a simplified nomogram to individualize digoxin dosing versus standard dosing practices in patients with heart failure.

Pharmacotherapy - 1 Nov 2014

DiDomenico Robert J, Bress Adam P, Na-Thalang Kwanta, Tsao Yvonne Y, Groo Vicki L, Deyo Kelly L, Patel Shitalben R, Bishop Jeffrey R, Bauman Jerry L

Abstract excerpt

STUDY OBJECTIVES: To compare the frequency of achieving a therapeutic serum digoxin concentration (SDC), defined as 0.5-0.9 ng/ml, by using a simplified nomogram to individualize digoxin dosing with standard dosing practices in patients with heart failure, and to characterize the relationship between genetic polymorphisms of the ABCB1 gene and SDC. DESIGN: Prospective study with a historical control group....

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Source

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Identifiers

PMID: 25164709
DOI: 10.1002/phar.1480
PMCID: PMC4227958

Genes

ABCB1

Variants

rs1128503
rs1128503
rs1128503

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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