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Article

High expression of LMTK3 is an independent factor indicating a poor prognosis in estrogen receptor α-positive breast cancer patients.

Japanese journal of clinical oncology - 1 Oct 2014

Asano Tomoko, Sato Shinya, Yoshimoto Nobuyasu, Endo Yumi, Hato Yukari, Dong Yu, Takahashi Satoru, Fujii Yoshitaka, Toyama Tatsuya

Abstract excerpt

OBJECTIVE: Over 70% of breast cancers are estrogen receptor alpha-positive, and endocrine therapy targeting estrogen action decreases mortality from breast cancer. Recently, a novel protein kinase that regulates estrogen receptor alpha activity, lemur tyrosine kinase-3, has been identified. In this study, we investigated whether messenger RNA expression and polymorphisms of the gene encoding the kinase, LMTK3,...

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Share to Carcinoma, Ductal, Breast
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Estrogen Receptor alpha

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Share to Real-Time Polymerase Chain Reaction

Share to Receptor, ErbB-2

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Source

Identifiers

PMID: 25163465
DOI: 10.1093/jjco/hyu113

Genes

LMTK3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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High expression of LMTK3 is an independent factor indicating a poor prognosis in estrogen receptor α-positive breast cancer patients.PMID 25163465Read ↗

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