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Haplotype diversity in the equine myostatin gene with focus on variants associated with race distance propensity and muscle fiber type proportions.

Animal genetics - 1 Dec 2014

Petersen Jessica L, Valberg Stephanie J, Mickelson James R, McCue Molly E

Abstract excerpt

Two variants in the equine myostatin gene (MSTN), including a T/C SNP in the first intron and a 227-bp SINE insertion in the promoter, are associated with muscle fiber type proportions in the Quarter Horse (QH) and with the prediction of race distance propensity in the Thoroughbred (TB). Genotypes from these loci, along with 18 additional variants surrounding MSTN, were examined in 301 horses of 14 breeds to...

Topics

Animals
Breeding
Gene Frequency
Genotype
Haplotypes
Horses
Introns
Muscle Fibers, Skeletal
Myostatin
Polymorphism, Single Nucleotide
Promoter Regions, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Short Interspersed Nucleotide Elements

Source

Open in PubMed Open full text

Identifiers

PMID: 25160752
DOI: 10.1111/age.12205
PMCID: PMC4211974

Genes

MSTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Haplotype diversity in the equine myostatin gene with focus on variants associated with race distance propensity and muscle fiber type proportions.PMID 25160752Read ↗

A genome-wide SNP-association study confirms a sequence variant (g.66493737C>T) in the equine myostatin (MSTN) gene as the most powerful predictor of optimum racing distance for Thoroughbred racehorses.Semantic proximity Read ↗

MSTN genotype (g.66493737C/T) association with speed indices in Thoroughbred racehorses.Semantic proximity Read ↗

Analysis of horse myostatin gene and identification of single nucleotide polymorphisms in breeds of different morphological types.Semantic proximity Read ↗

Horses for courses: a DNA-based test for race distance aptitude in thoroughbred racehorses.Semantic proximity Read ↗

Identification of the myostatin locus (MSTN) as having a major effect on optimum racing distance in the Thoroughbred horse in the USA.Semantic proximity Read ↗

Characterization of Partial Sequence of Myostatin Gene Exon 2 along with SNP detection in Indian Horse Breeds (Equus caballus).Semantic proximity Read ↗

A sequence polymorphism in MSTN predicts sprinting ability and racing stamina in thoroughbred horses.Semantic proximity Read ↗

Genome-wide analysis reveals selection for important traits in domestic horse breeds.Semantic proximity Read ↗

A highly prevalent SINE mutation in the myostatin (MSTN) gene promoter is associated with low circulating myostatin concentration in Thoroughbred racehorses.Semantic proximity Read ↗

Conformation Traits and Gaits in the Icelandic Horse are Associated with Genetic Variants in Myostatin (MSTN).Semantic proximity Read ↗

Putative regulation mechanism for the MSTN gene by a CpG island generated by the SINE marker Ins227bp.Semantic proximity Read ↗

Sequence variants at the myostatin gene locus influence the body composition of Thoroughbred horses.Semantic proximity Read ↗

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