Article
Sequence variants at the myostatin gene locus influence the body composition of Thoroughbred horses.
The Journal of veterinary medical science - 1 Dec 2011
Tozaki Teruaki, Sato Fumio, Hill Emmeline W, Miyake Takeshi, Endo Yoshiro, Kakoi Hironaga, Gawahara Hitoshi, Hirota Kei-ichi, Nakano Yasuko, Nambo Yasuo, Kurosawa Masahiko
Abstract excerpt
Myostatin is a member of the transforming growth factor-β family with a key role in inhibition of muscle growth by negative regulation of both myoblast proliferation and differentiation. Recently, a genomic region on ECA18, which includes the MSTN gene, was identified as a candidate region influencing racing performance in Thoroughbreds. In this study, four SNPs on ECA18, g.65809482T>C, g.65868604G>T,...
Topics
- Animals
- Body Composition
- Female
- Genotype
- Horses
- Male
- Myostatin
- Physical Conditioning, Animal
- Polymorphism, Single Nucleotide