Article
Analysis of horse myostatin gene and identification of single nucleotide polymorphisms in breeds of different morphological types.
Journal of biomedicine & biotechnology - 1 Jan 2010
Dall'Olio Stefania, Fontanesi Luca, Nanni Costa Leonardo, Tassinari Marco, Minieri Laura, Falaschini Adalberto
Abstract excerpt
Myostatin (MSTN) is a negative modulator of muscle mass. We characterized the horse (Equus caballus) MSTN gene and identified and analysed single nucleotide polymorphisms (SNPs) in breeds of different morphological types. Sequencing of coding, untranslated, intronic, and regulatory regions of MSTN gene in 12 horses from 10 breeds revealed seven SNPs: two in the promoter, four in intron 1, and one in intron 2. The...
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