PPARγ2 Pro12Ala polymorphism is associated with sustained virological response in HIV/HCV-coinfected patients under HCV therapy.

doi:10.1097/QAI.0000000000000282

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Article

PPARγ2 Pro12Ala polymorphism is associated with sustained virological response in HIV/HCV-coinfected patients under HCV therapy.

Journal of acquired immune deficiency syndromes (1999) - 1 Oct 2014

Fernández-Rodríguez Amanda, Berenguer Juan, Rallón Norma, Jiménez-Sousa María A, López Juan Carlos, Soriano Vicente, García-Álvarez Mónica, Cosín Jaime, Martínez Paula, Guzmán-Fulgencio María, Miralles Pilar, Miguel Benito José, Resino Salvador

Abstract excerpt

OBJECTIVES: To analyze whether peroxisome proliferator-activated receptor gamma (PPARγ2) rs1801282 (Pro12Ala) polymorphism is associated with the response to pegylated-interferon-alpha plus ribavirin treatment in HIV/hepatitis C virus (HCV)-coinfected patients, and whether it is able to predict the outcome of HCV treatment. DESIGN: Retrospective follow-up study. METHODS: Two hundred eighty-five naive patients,...

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PMID: 25072612
DOI: 10.1097/QAI.0000000000000282

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