Article
Extracellular water and blood pressure in adults with growth hormone (GH) deficiency: a genotype-phenotype association study.
PloS one - 1 Jan 2014
Barbosa Edna J L, Glad Camilla A M, Nilsson Anna G, Bosaeus Niklas, Nyström Helena Filipsson, Svensson Per-Arne, Bengtsson Bengt-Åke, Nilsson Staffan, Bosaeus Ingvar, Boguszewski Cesar Luiz, Johannsson Gudmundur
Abstract excerpt
OBJECTIVES: Growth hormone deficiency (GHD) in adults is associated with decreased extracellular water volume (ECW). In response to GH replacement therapy (GHRT), ECW increases and blood pressure (BP) reduces or remains unchanged. Our primary aim was to study the association between polymorphisms in genes related to renal tubular function with ECW and BP before and 1 year after GHRT. The ECW measures using...
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