Bartter syndrome: causes, diagnosis, and treatment

Abstract excerpt

Bartter syndrome is an inherited renal tubular disorder caused by a defective salt reabsorption in the thick ascending limb of loop of Henle, resulting in salt wasting, hypokalemia, and metabolic alkalosis. Mutations of several genes encoding the transporters and channels involved in salt reabsorption in the thick ascending limb cause different types of Bartter syndrome. A poor phenotype-genotype relationship due...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Ion Transport and Channel Regulation
• Share to Ion channel regulation and function
• Share to Electrolyte and hormonal disorders