Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Does dietary folic acid supplementation in mouse NTD models affect neural tube development or gamete preference at fertilization?

BMC genetics - 27 Aug 2014

Nakouzi Ghunwa A, Nadeau Joseph H

Abstract excerpt

BACKGROUND: Neural tube defects (NTDs) are the second most common birth defect in humans. Dietary folic acid (FA) supplementation effectively and safely reduces the incidence of these often debilitating congenital anomalies. FA plays an established role in folate and homocysteine metabolism, but the means by which it suppresses occurrence of NTDs is not understood. In addition, many cases remain resistant to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein B-100
Share to Apolipoproteins B
Share to Embryo Loss

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fertilization

Share to Folic Acid

Share to Germ Cells

Share to Neural Tube

Share to Neural Tube Defects

Source

Open in PubMed Open full text

Identifiers

PMID: 25154628
DOI: 10.1186/s12863-014-0091-x
PMCID: PMC4151023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Does dietary folic acid supplementation in mouse NTD models affect neural tube development or gamete preference at fertilization?PMID 25154628Read ↗

Folate deficiency increases the incidence of dolutegravir-associated foetal defects in a mouse pregnancy modelSemantic proximity Read ↗

Mouse models of neural tube defects: Investigating preventive mechanismsSemantic proximity Read ↗

Micronutrient imbalance and common phenotypes in neural tube defectsSemantic proximity Read ↗

Methylenetetrahydrofolate reductase deficiency and low dietary folate increase embryonic delay and placental abnormalities in miceSemantic proximity Read ↗

Folic acid supplementation can adversely affect murine neural tube closure and embryonic survival.Semantic proximity Read ↗

Insights into prevention of human neural tube defects by folic acid arising from consideration of mouse mutantsSemantic proximity Read ↗

Pathophysiology, prevention, and potential treatment of neural tube defectsSemantic proximity Read ↗

Mouse models for neural tube closure defects.Semantic proximity Read ↗

Moderate maternal folic acid supplementation ameliorates adverse embryonic and epigenetic outcomes associated with assisted reproduction in a mouse modelSemantic proximity Read ↗

Etiology and pathogenesis of human neural tube defectsSemantic proximity Read ↗

Mouse as a model for multifactorial inheritance of neural tube defects.Semantic proximity Read ↗

Dolutegravir-induced neural tube defects in mice are folate responsiveSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.