Article
Voltage-gated calcium channels in the human adrenal and primary aldosteronism.
The Journal of steroid biochemistry and molecular biology - 1 Oct 2014
Felizola Saulo J A, Maekawa Takashi, Nakamura Yasuhiro, Satoh Fumitoshi, Ono Yoshikiyo, Kikuchi Kumi, Aritomi Shizuka, Ikeda Keiichi, Yoshimura Michihiro, Tojo Katsuyoshi, Sasano Hironobu
Abstract excerpt
Calcium channel blockers can efficiently be used in the treatment of primary aldosteronism (PA) related hypertension, but details on the localization of calcium channel (CC) in the human adrenal and its disorders, including PA, have remained unclear. Therefore, in this study we analyzed the known α subunits of L-, N- and T-type CCs in 74 adrenocortical aldosterone-producing adenomas (APA) and 16...
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