Article
Epigenetic mechanisms and the relationship to childhood asthma.
The European respiratory journal - 1 Oct 2010
Kabesch M, Michel S, Tost J
Abstract excerpt
Epigenetic mechanisms mediate genomic adaption to the environment and epigenetic alterations can contribute to the development of disease phenotypes, as can genetic variants. A variety of molecular mechanisms are involved in epigenetic regulation, including post-transcriptional histone modifications, histone variants, ATP-dependent chromatin remodelling complexes, polycomb/trithorax protein complexes, small and...
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