Article
The ITGAV-rs3911238 polymorphism is associated with disease activity in rheumatoid arthritis.
Iranian journal of allergy, asthma, and immunology - 1 Oct 2014
Shakiba Ebrahim, Tavilani Haidar, Goodarzi Mohamad Taghi, Kiani Amir, Pourmotabbed Tayehbbeh, Vaisi-Raygani Asad
Abstract excerpt
Evidences indicate that angiogenesis is an important process in the development of destructive synovial tissue in rheumatoid arthritis (RA). Recently, it has been shown that the polymorphism of the integrin-αv subunit encoded by the ITGAV gene plays a role in angiogenesis and is considered as RA susceptibility loci. This study investigated association of four single nucleotide polymorphisms (SNPs) in ITGAV with...
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