Article
The rs3768777-G allele of ITGAV gene is associated with rheumatoid arthritis.
Rheumatology international - 1 May 2014
Koca Suleyman Serdar, Kara Murat, Ozgen Metin, Dagli Mustafa Necati, Gozel Nevzat, Yolbas Servet, Gundogdu Baris, Kargun Kursat, Isik Ahmet
Abstract excerpt
Integrin αvβ3 (vitronectin receptor) plays a prominent role in angiogenesis, a key pathogenic feature of rheumatoid arthritis (RA). Moreover, integrin αV (ITGAV) subunit gene has been associated with a susceptibility to RA. The aim of the present study was to detect the potential association betw...
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