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Assessment of Angiopoietin-2 Single Nucleotide Polymorphism in Patients with Rheumatoid Arthritis.

Inflammation - 1 Jun 2023

Nasef Samah Ismail, Ellawindy Alia, Askar Aya Mohamed, Hashem Asmaa AbdelKreem, Omar Hanan Hassan

Abstract excerpt

Rheumatoid arthritis (RA) is an inflammatory autoimmune disease that destroys joint cartilage and causes disability. Synovial inflammation, with angiogenesis, is an early event in the progression of the disease. Angiopoietin 2 (ANGPT2) is a cytokine with both inflammatory and angiogenic effects. Many genes can influence RA susceptibility and disease activity. The aim is to assess the relationship between ANGPT2...

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PMID: 36562898
DOI: 10.1007/s10753-022-01773-3

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