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Article

Identification of mutant alleles of JAK3 in pediatric patients with acute lymphoblastic leukemia.

Leukemia & lymphoma - 1 May 2015

Yin Changhong, Sandoval Claudio, Baeg Gyeong-Hun

Abstract excerpt

Children with acute lymphoblastic leukemia (ALL) have an 80% chance of long-term survival. Despite the high rate of cure, children relapse, and recurrent ALL is difficult to cure with chemotherapeutic regimens. Therefore, improved biological understanding of ALL and the development of rationally designed therapeutics targeting molecules associated with the pathogenesis of ALL are essential. We identified missense...

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Source

Identifiers

PMID: 25146434
DOI: 10.3109/10428194.2014.957204

Genes

JAK3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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