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Article

Assembly and Architecture of the EBV B Cell Entry Triggering Complex

21 Aug 2014

Abstract excerpt

Epstein-Barr Virus (EBV) is an enveloped double-stranded DNA virus of the gammaherpesvirinae sub-family that predominantly infects humans through epithelial cells and B cells. Three EBV glycoproteins, gH, gL and gp42, form a complex that targets EBV infection of B cells. Human leukocyte antigen (HLA) class II molecules expressed on B cells serve as the receptor for gp42, triggering membrane fusion and virus...

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PMID: 25144748
DOI: 10.1371/journal.ppat.1004309

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