Article
Cleavage and secretion of Epstein-Barr virus glycoprotein 42 promote membrane fusion with B lymphocytes.
Journal of virology - 1 Jul 2009
Sorem Jessica, Jardetzky Theodore S, Longnecker Richard
Abstract excerpt
Epstein-Barr virus (EBV) membrane glycoprotein 42 (gp42) is required for viral entry into B lymphocytes through binding to human leukocyte antigen (HLA) class II on the B-cell surface. EBV gp42 plays multiple roles during infection, including acting as a coreceptor for viral entry into B cells, binding to EBV glycoprotein H (gH) and gL during the process of membrane fusion, and blocking T-cell recognition of HLA...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
