Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Follistatin-Like 1 Attenuates Apoptosis via Disco-Interacting Protein 2 Homolog A/Akt Pathway After Middle Cerebral Artery Occlusion in Rats

20 Aug 2014

Abstract excerpt

BACKGROUND AND PURPOSE: Follistatin-like 1 (FSTL1), an extracellular glycoprotein, has been reported to decrease apoptosis in ischemic cardiac diseases, but its effect in ischemic stroke has not been examined. We hypothesized that recombinant FSTL1 attenuates neuronal apoptosis through its receptor disco-interacting protein 2 homolog A (DIP2A) and the Akt pathway after middle cerebral artery occlusion (MCAO) in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neurogenesis and neuroplasticity mechanisms
Share to Pituitary Gland Disorders and Treatments
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25139876
DOI: 10.1161/strokeaha.114.006092

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Follistatin-Like 1 Attenuates Apoptosis via Disco-Interacting Protein 2 Homolog A/Akt Pathway After Middle Cerebral Artery Occlusion in RatsPMID 25139876Read ↗

miR-212-5p protects the brain against ischemic damage in rats and its function is regulated by the lncfos/miR-212-5p/CASP7 axisSemantic proximity Read ↗

MicroRNA-29c Correlates with Neuroprotection Induced by FNS by Targeting Both Birc2 and Bak1 in Rat Brain after Stroke.Semantic proximity Read ↗

Direct neuronal protection by the protease-activated receptor PAR4 antagonist ML354 after experimental stroke in miceSemantic proximity Read ↗

C5aR1 mediates progression of inflammatory responses in brain of rats after ischemia and reperfusionSemantic proximity Read ↗

STAT1 is activated in neurons after ischemia and contributes to ischemic brain injury.Semantic proximity Read ↗

Fas/CD95 regulatory protein Faim2 is neuroprotective after transient brain ischemia.Semantic proximity Read ↗

Sirtuins 1 and 2 in the Acute Period After Photothrombotic Stroke: Expression, Localization and Involvement in ApoptosisSemantic proximity Read ↗

[IMMP2L gene mutation activates mitochondrial apoptotic pathway to aggravate cerebral ischemic injury in mice].Semantic proximity Read ↗

Immp2l Mutation Induces Mitochondrial Membrane Depolarization and Complex III Activity Suppression after Middle Cerebral Artery Occlusion in Mice.Semantic proximity Read ↗

Survivin Is a Transcriptional Target of STAT3 Critical to Estradiol Neuroprotection in Global IschemiaSemantic proximity Read ↗

Kallikrein Gene Transfer Protects Against Ischemic Stroke by Promoting Glial Cell Migration and Inhibiting ApoptosisSemantic proximity Read ↗

Genetic Mutation of GluN2B Protects Brain Cells Against Stroke Damages.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.