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[IMMP2L gene mutation activates mitochondrial apoptotic pathway to aggravate cerebral ischemic injury in mice].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology - 1 Jul 2021

Cheng Zhengyi, Mi Xiaojuan, Zhang Zijing, Ma Yi

Abstract excerpt

Objective To investigate the effect of inner mitochondrial membrane peptidase 2-like (IMMP2L) gene mutation on cerebral ischemic injury and its mechanism. Methods The cerebral ischemia/reperfusion (I/R) model was established in wild-type (WT) mice and mice with IMMP2L gene mutation (IMMP2L+/-) by middle cerebral artery occlusion (MCAO), and cortical tissues were collected at 0, 1, 5 and 24 hours after...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34140073

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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