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Article

Modulation of chemotherapeutic drug resistance in neuroblastoma SK-N-AS cells by the neural apoptosis inhibitory protein and miR-520f.

International journal of cancer - 1 Apr 2015

Harvey Harry, Piskareva Olga, Creevey Laura, Alcock Leah C, Buckley Patrick G, O'Sullivan Maureen J, Segura Miguel F, Gallego Soledad, Stallings Raymond L, Bray Isabella M

Abstract excerpt

The acquisition of multidrug resistance is a major impediment to the successful treatment of neuroblastoma, a clinically heterogeneous cancer accounting for ∼15% of all pediatric cancer deaths. The MYCN transcription factor, whose gene is amplified in ∼30% of high-risk neuroblastoma cases, influences drug resistance by regulating a cadre of genes, including those involved with drug efflux, however, other...

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Share to Antineoplastic Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Comparative Genomic Hybridization

Share to Drug Resistance, Neoplasm

Share to Gene Expression Regulation, Neoplastic

Share to MicroRNAs

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Source

Identifiers

PMID: 25137037
DOI: 10.1002/ijc.29144

Genes

NAIP
MYCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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