Article
Stem Cell Pathways and Notch Signalling an Emerging Role in the Development of Acquired Drug Resistance in Neuroblastoma
2021-08-26
Abstract excerpt
<title>Abstract</title> <p>BackgroundNeuroblastoma is a paediatric tumour that develops from embryonal neural crest cells that give rise to the sympathetic nervous system. Aggressive high-risk disease remains a clinical challenge and despite multi-modal therapy, survival rates are poor. Most neuroblastomas initially respond well to induction chemotherapy however, 50-60% of patients with high risk disease will rel...
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Identifiers and source
- Literature Corpus work
- fe4c53d6-8821-5d29-838d-2fd1bc309267
- DOI
- 10.21203/rs.3.rs-827092/v1