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Article

Characterizing of functional human coding RNA editing from evolutionary, structural, and dynamic perspectives.

Proteins - 1 Nov 2014

Solomon Oz, Bazak Lily, Levanon Erez Y, Amariglio Ninette, Unger Ron, Rechavi Gideon, Eyal Eran

Abstract excerpt

A-to-I RNA editing has been recently shown to be a widespread phenomenon with millions of sites spread in the human transcriptome. However, only few are known to be located in coding sequences and modify the amino acid sequence of the protein product. Here, we used high-throughput data, variant prediction tools, and protein structural information in order to find structural and functional preferences for coding...

Read the complete abstract on PubMed

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Share to Adaptor Proteins, Signal Transducing
Share to Amino Acids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Databases, Protein

Share to Kv1.1 Potassium Channel

Share to Protein Interaction Domains and Motifs

Share to Receptors, AMPA

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Source

Identifiers

PMID: 25136968
DOI: 10.1002/prot.24672

Genes

CCNI
COPA
GIPC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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