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Article

The molecular phenotype of endocapillary proliferation: novel therapeutic targets for IgA nephropathy.

PloS one - 1 Jan 2014

Hodgin Jeffrey B, Berthier Celine C, John Rohan, Grone Elisabeth, Porubsky Stefan, Gröne Hermann-Josef, Herzenberg Andrew M, Scholey James W, Hladunewich Michelle, Cattran Daniel C, Kretzler Matthias, Reich Heather N

Abstract excerpt

IgA nephropathy (IgAN) is a clinically and pathologically heterogeneous disease. Endocapillary proliferation is associated with higher risk of progressive disease, and clinical studies suggest that corticosteroids mitigate this risk. However, corticosteroids are associated with protean cellular effects and significant toxicity. Furthermore the precise mechanism by which they modulate kidney injury in IgAN is not...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Glomerulonephritis, IGA

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Identifiers

PMID: 25133636
DOI: 10.1371/journal.pone.0103413
PMCID: PMC4136785

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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