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Article

Haplotype counting by next-generation sequencing for ultrasensitive human DNA detection.

The Journal of molecular diagnostics : JMD - 1 Sept 2014

Debeljak Marija, Freed Donald N, Welch Jane A, Haley Lisa, Beierl Katie, Iglehart Brian S, Pallavajjala Aparna, Gocke Christopher D, Leffell Mary S, Lin Ming-Tseh, Pevsner Jonathan, Wheelan Sarah J, Eshleman James R

Abstract excerpt

Human identity testing is critical to the fields of forensics, paternity, and hematopoietic stem cell transplantation. Most bone marrow (BM) engraftment testing currently uses microsatellites or short tandem repeats that are resolved by capillary electrophoresis. Single-nucleotide polymorphisms (SNPs) are theoretically a better choice among polymorphic DNA; however, ultrasensitive detection of SNPs using...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 25132481
DOI: 10.1016/j.jmoldx.2014.04.003
PMCID: PMC5691345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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