Article
Approaches for identifying multiple-SNP haplotype blocks for use in human identification.
Legal medicine (Tokyo, Japan) - 1 Sept 2015
Hiroaki Nakahara, Koji Fujii, Tetsushi Kitayama, Kazumasa Sekiguchi, Hiroaki Nakanishi, Kazuyuki Saito
Abstract excerpt
Single nucleotide polymorphism (SNP) discrimination effectiveness is low due to the bi-allelic nature of SNPs, and large numbers of loci must be analyzed for human identification in forensic casework. To resolve these issues, the authors support the use of multiple SNP haplotypes that will generate many haplotypes based on the combination of SNP alleles. First, 27 regions were selected from the JSNP database...
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