Article
Mast cell phenotype in benign and malignant tumors of the prostate.
Polish journal of pathology : official journal of the Polish Society of Pathologists - 1 Jun 2014
Globa T, Saptefrţi L, Ceauşu R A, Gaje P, Cimpean A M, Raica M
Abstract excerpt
The molecular phenotypic heterogeneity of mast cells (MCs) makes them attractive as potential therapeutic targets in anti-cancer adjuvant therapy. Mast cell aggregations observed in tumors suggested their involvement in tumor pathogenesis. Despite several studies using mast cell tryptase, MCs' involvement in the progression of prostate tumors has not been demonstrated. The aim of our study was to identify and...
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