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Article

Differential mast cell phenotypes in benign versus cancer tissues and prostate cancer oncologic outcomes.

The Journal of pathology - 1 Apr 2021

Hempel Sullivan Heidi, Maynard Janielle P, Heaphy Christopher M, Lu Jiayun, De Marzo Angelo M, Lotan Tamara L, Joshu Corinne E, Sfanos Karen S

Abstract excerpt

We reported previously that high numbers of mast cells in benign (extra-tumoral) regions of the prostate are associated with worse outcomes after radical prostatectomy including biochemical recurrence and the development of metastases. Herein, with a cohort of 384 men, we performed mast cell subtyping and report that higher minimum number of the tryptase-only (MCT ) subset of extra-tumoral mast cells is...

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PMID: 33338262
DOI: 10.1002/path.5606

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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