Article
Resistance prediction in AML: analysis of 4601 patients from MRC/NCRI, HOVON/SAKK, SWOG and MD Anderson Cancer Center.
Leukemia - 1 Feb 2015
Walter R B, Othus M, Burnett A K, Löwenberg B, Kantarjian H M, Ossenkoppele G J, Hills R K, Ravandi F, Pabst T, Evans A, Pierce S R, Vekemans M-C, Appelbaum F R, Estey E H
Abstract excerpt
Therapeutic resistance remains the principal problem in acute myeloid leukemia (AML). We used area under receiver-operating characteristic curves (AUCs) to quantify our ability to predict therapeutic resistance in individual patients, where AUC=1.0 denotes perfect prediction and AUC=0.5 denotes a coin flip, using data from 4601 patients with newly diagnosed AML given induction therapy with 3+7 or more intense...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.