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Article

IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions.

World journal of gastroenterology - 7 Aug 2014

Naito Takafumi, Nosho Katsuhiko, Ito Miki, Igarashi Hisayoshi, Mitsuhashi Kei, Yoshii Shinji, Aoki Hironori, Nomura Masafumi, Sukawa Yasutaka, Yamamoto Eiichiro, Adachi Yasushi, Takahashi Hiroaki, Hosokawa Masao, Fujita Masahiro, Takenouchi Toshinao, Maruyama Reo, Suzuki Hiromu, Baba Yoshifumi, Imai Kohzoh, Yamamoto Hiroyuki, Ogino Shuji, Shinomura Yasuhisa

Abstract excerpt

AIM: To investigate insulin-like growth factor 2 (IGF2) differentially methylated region (DMR)0 hypomethylation in relation to clinicopathological and molecular features in colorectal serrated lesions. METHODS: To accurately analyze the association between the histological types and molecular features of each type of serrated lesion, we consecutively collected 1386 formalin-fixed paraffin-embedded tissue...

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Identifiers

PMID: 25110432
DOI: 10.3748/wjg.v20.i29.10050
PMCID: PMC4123334

Genes

IGF2
HGD
BRAF
KRAS
MGMT
MLH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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