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Article

Comparative analysis of optogenetic actuators in cultured astrocytes.

Cell calcium - 1 Sept 2014

Figueiredo Melina, Lane Samantha, Stout Randy F, Liu Beihui, Parpura Vladimir, Teschemacher Anja G, Kasparov Sergey

Abstract excerpt

Astrocytes modulate synaptic transmission via release of gliotransmitters such as ATP, glutamate, D-serine and L-lactate. One of the main problems when studying the role of astrocytes in vitro and in vivo is the lack of suitable tools for their selective activation. Optogenetic actuators can be used to manipulate astrocytic activity by expression of variants of channelrhodopsin-2 (ChR2) or other optogenetic...

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Identifiers

PMID: 25109549
DOI: 10.1016/j.ceca.2014.07.007
PMCID: PMC4169180

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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