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Article

MicroRNA Regulates Vascular Endothelial Growth Factor Expression in Chondrosarcoma Cells

8 Aug 2014

Abstract excerpt

BACKGROUND: Systemic treatments to prevent or treat chondrosarcoma metastasis are lacking and targeted therapy has yet to be developed. Hypoxia develops in tumors as they grow and hypoxia-related alterations in gene expression underlie some of the traits of cancer. One critical trait is the ability to induce sustained angiogenesis, which is usually related to expression of vascular endothelial growth factor...

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PMID: 25106798
DOI: 10.1007/s11999-014-3842-0

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