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Article

The impact of a BRCA2 mutation on mortality from screen-detected prostate cancer.

British journal of cancer - 9 Sept 2014

Akbari M R, Wallis C J D, Toi A, Trachtenberg J, Sun P, Narod S A, Nam R K

Abstract excerpt

BACKGROUND: Men with a BRCA2 mutation face an increased risk of prostate cancer. These cancers tend to have an aggressive nature and it has not yet been demonstrated that regular screening of BRCA2 carriers is associated with improved survival. METHODS: We identified 4187 men who underwent a prostate cancer biopsy for an elevated PSA or an abnormal digital rectal examination between 1998 and 2010. We screened the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25101567
DOI: 10.1038/bjc.2014.428
PMCID: PMC4453856

Genes

BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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