Article
Evolutionary origin of bone morphogenetic protein 15 and growth and differentiation factor 9 and differential selective pressure between mono- and polyovulating species.
Biology of reproduction - 1 Oct 2014
Monestier Olivier, Servin Bertrand, Auclair Sylvain, Bourquard Thomas, Poupon Anne, Pascal Géraldine, Fabre Stéphane
Abstract excerpt
Bone morphogenetic protein 15 (BMP15) and growth and differentiation factor 9 (GDF9) are TGFbeta-like oocyte-derived growth factors involved in ovarian folliculogenesis as critical regulators of many granulosa cell processes and ovulation rate. Ovarian phenotypic effect caused by alterations in B...
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